Дисгерминома — редкая герминогенная опухоль у беременной. Клиническое наблюдение и современное состояние вопроса по данным литературы
Аннотация
В статье приведен редкий случай дисгерминомы у беременной. В связи с единичными наблюдениями данной патологии не существует доказательно обоснованных рекомендаций по ведению таких больных. Представлены результаты обследования пациентки, описана ультразвуковая характеристика опухоли. Проведено хирургическое лечение в объеме односторонней лапароскопической овариоэктомии. Отображены результаты иммуногистохимического исследования опухоли. Беременность завершилась рождением живого доношенного плода. Проведен анализ современного состояния вопроса по данным литературы, в котором отражены вопросы классификации, патогенеза дисгерминомы, ультразвуковые признаки опухоли, существующие алгоритмы диагностики и лечения, особенности течения заболевания у беременных. Результаты клинического наблюдения сопоставлены с литературными данными.
Литература
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3. Demura TA, Nikanorova AV. Germinogenic hormone-producing ovarian tumors. Al'manakh Prostranstvo i Vremya. 2018;16(3-4):1-12 (In Russ.). doi: 10.24411/2227-9490-2018-12071].
4. Zhukovskaya EV. Fertility problems in patients with germ cell tumors. Rossiiskii onkologicheskii zhurnal. 2016;21(5):275-280 (In Russ.). doi:10.18821/1028-9984-2016-21-5-275-280.
5. Solopova AE, Sologub YuN, Solopova AG, Makatsariya AD. Ovarian germ cell tumors – a modern approach to the problem. Zhurnal akusherstva i zhenskikh boleznei. 2016;LXV(2):4-15 (In Russ.). doi:10.17816/jowd6524-15.
6. Streltsova O, Davidova I, Zhordania K, Kuznetsov V, Tjulandin S. Fertility-Sparing Surgical. Management of Malignant Ovarian Germ Cell Tumours: Two Case Reports. Zlokachestvennye opukholi. 2012;2(1):22-28 (In Russ.).
7. Streltzova ON, Fedyanin MYu, Tryakin AA, Bulanov AA, Zhordania VV, Tyulandin SA. Ovarian dysgerminomas: treatment experience of the N.N.Blokhin CRC RAMS Opukholi zhenskoi reproduktivnoi sistemy. 2008;1:52-56.
8. Chekini DA, Tryakin A A, Fedyanin MY, Zhordania KI, Pokataev IA, Bulanov AA, Zakharova TI, Tjulandin SA. Reproductive function in patients with malignant ovarian germ cell tumours. Malignant tumours. 2017;7(2):47-53 (In Russ.). doi: 10.18027 / 2224–5057–2017–2–47-53.
9. Chekini DA, Tryakin AA, Fedyanin MY, Pokataev IA, Zhordania KI, Akhmedova MD, Zakharova TI, Tjulandin SA. Prognostic factors and effectiveness of the treatment in patients of ovarian germ cell tumors. Onkoginekologia, 2017, 2017;2(22):52-63 (In Russ.). doi: 10.1093/annonc/mdw374.29.
10. Chekiny DA, Tryakin AA, Fedyanin MY, Tulyandin SA. Malignant ovarian germ cell tumors: epidemiology, clinical features, diagnosis, treatment. Vestnik FGBU "RONTs im. N.N. Blokhina". 2016;27(2):39-46 (In Russ.).
11. Kurman RJ, Саrcanqiu ML, Herrington CS, Young RH. WHO Classification of Tumours of Female Reproductive Organs. Fourth Edition. IARS: Lyon; 2014.
12. Malek M, Pourashraf M, Mousavi AS, Rahmani M. Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI. Asian Pac J Cancer Prev. 2015;16 (8):3407-3412. doi: 10.7314/APJCP.2015.16.8.3407.
13. Nogales FF, Dulcey I, Preda O. Germ cell tumors of the ovary An update. Arch Pathol Lab Med. 2014;138:351-362. doi: 10.5858/arpa.2012-0547-RA.
14. Prat J. FIGO’s staging classification for cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet. 2014;124:1-5. doi: 10.1016/j.ijgo.2013.10.001.
15. Sadler M. Management of female malignant ovarian germ cell tumours. The Obstetrician & Gynaecologist. 2017;19(1):86. doi: 10.1111/tog.12356.
16. Shaaban AM, Rezvani M, Elsayes KM, Baskin H. Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. RadioGraphics. 2014;34:777-801. doi: 10.1148/rg.343130067.
17. Solheim O, Tropé CG, Rokkones E., Kærn J, Paulsen T, Salvesen HB, Hagen B, Vereide AB., Fosså SD. Fertility and gonadal function after adjuvant therapy in women diagnosed with a malignant ovarian germ cell tumor (MOGCT) during the “cisplatin era”. Gynecologic Oncology. 2015;136(2):224-229. doi: 10.1016/j.ygyno.2014.12.010.
18. Tjulandin SA, Tryakin AA, Fedyanin MJu. Germ cell tumors. Practical oncology. 2017;18(2):161-173. doi: 10.31917/1802161.
2. Demidov VN, Gus AI, Adamyan LV, Lipatenkova YuI. Echography of pelvic organs in women. Issue. 4. Borderline tumors, cancer and rare ovarian tumors : a Practical guide. M.: BINOM; 2017 (In Russ.).
3. Demura TA, Nikanorova AV. Germinogenic hormone-producing ovarian tumors. Al'manakh Prostranstvo i Vremya. 2018;16(3-4):1-12 (In Russ.). doi: 10.24411/2227-9490-2018-12071].
4. Zhukovskaya EV. Fertility problems in patients with germ cell tumors. Rossiiskii onkologicheskii zhurnal. 2016;21(5):275-280 (In Russ.). doi:10.18821/1028-9984-2016-21-5-275-280.
5. Solopova AE, Sologub YuN, Solopova AG, Makatsariya AD. Ovarian germ cell tumors – a modern approach to the problem. Zhurnal akusherstva i zhenskikh boleznei. 2016;LXV(2):4-15 (In Russ.). doi:10.17816/jowd6524-15.
6. Streltsova O, Davidova I, Zhordania K, Kuznetsov V, Tjulandin S. Fertility-Sparing Surgical. Management of Malignant Ovarian Germ Cell Tumours: Two Case Reports. Zlokachestvennye opukholi. 2012;2(1):22-28 (In Russ.).
7. Streltzova ON, Fedyanin MYu, Tryakin AA, Bulanov AA, Zhordania VV, Tyulandin SA. Ovarian dysgerminomas: treatment experience of the N.N.Blokhin CRC RAMS Opukholi zhenskoi reproduktivnoi sistemy. 2008;1:52-56.
8. Chekini DA, Tryakin A A, Fedyanin MY, Zhordania KI, Pokataev IA, Bulanov AA, Zakharova TI, Tjulandin SA. Reproductive function in patients with malignant ovarian germ cell tumours. Malignant tumours. 2017;7(2):47-53 (In Russ.). doi: 10.18027 / 2224–5057–2017–2–47-53.
9. Chekini DA, Tryakin AA, Fedyanin MY, Pokataev IA, Zhordania KI, Akhmedova MD, Zakharova TI, Tjulandin SA. Prognostic factors and effectiveness of the treatment in patients of ovarian germ cell tumors. Onkoginekologia, 2017, 2017;2(22):52-63 (In Russ.). doi: 10.1093/annonc/mdw374.29.
10. Chekiny DA, Tryakin AA, Fedyanin MY, Tulyandin SA. Malignant ovarian germ cell tumors: epidemiology, clinical features, diagnosis, treatment. Vestnik FGBU "RONTs im. N.N. Blokhina". 2016;27(2):39-46 (In Russ.).
11. Kurman RJ, Саrcanqiu ML, Herrington CS, Young RH. WHO Classification of Tumours of Female Reproductive Organs. Fourth Edition. IARS: Lyon; 2014.
12. Malek M, Pourashraf M, Mousavi AS, Rahmani M. Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI. Asian Pac J Cancer Prev. 2015;16 (8):3407-3412. doi: 10.7314/APJCP.2015.16.8.3407.
13. Nogales FF, Dulcey I, Preda O. Germ cell tumors of the ovary An update. Arch Pathol Lab Med. 2014;138:351-362. doi: 10.5858/arpa.2012-0547-RA.
14. Prat J. FIGO’s staging classification for cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet. 2014;124:1-5. doi: 10.1016/j.ijgo.2013.10.001.
15. Sadler M. Management of female malignant ovarian germ cell tumours. The Obstetrician & Gynaecologist. 2017;19(1):86. doi: 10.1111/tog.12356.
16. Shaaban AM, Rezvani M, Elsayes KM, Baskin H. Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. RadioGraphics. 2014;34:777-801. doi: 10.1148/rg.343130067.
17. Solheim O, Tropé CG, Rokkones E., Kærn J, Paulsen T, Salvesen HB, Hagen B, Vereide AB., Fosså SD. Fertility and gonadal function after adjuvant therapy in women diagnosed with a malignant ovarian germ cell tumor (MOGCT) during the “cisplatin era”. Gynecologic Oncology. 2015;136(2):224-229. doi: 10.1016/j.ygyno.2014.12.010.
18. Tjulandin SA, Tryakin AA, Fedyanin MJu. Germ cell tumors. Practical oncology. 2017;18(2):161-173. doi: 10.31917/1802161.
Опубликована
2019-10-08
Как цитировать
ЧЕРНЯЕВА, Ю. В..
Дисгерминома — редкая герминогенная опухоль у беременной. Клиническое наблюдение и современное состояние вопроса по данным литературы.
Новообразование, [S.l.], v. 11, n. 3, p. 103 - 109, окт. 2019.
ISSN 2521-117X.
Доступно на: <http://donetsk-onco.com/neoplasm/index.php/Neoplasm/article/view/288>. Дата доступа: 20 апр. 2024
doi: https://doi.org/10.26435/neoplasm.v11i3.288.
Раздел
Оригинальные статьи
