Проблемы лечения рака прямой кишки у больных старческого возраста

  • С. Э. Золотухин 1)ГОО ВПО «Донецкий национальный медицинский университет им. М Горького 2)РОЦ «Республиканский онкологический центр» им. Профессора Г.В. Бондаря МЗ ДНР
  • А. Д. Амджад 2)РОЦ «Республиканский онкологический центр» им. Профессора Г.В. Бондаря г. Донецк 83000 ул. Полоцкая 2А
  • А. Понсе Прадо 2)РОЦ «Республиканский онкологический центр» им. Профессора Г.В. Бондаря г. Донецк 83000 ул. Полоцкая 2А
  • А. Н. Заика 1)ГОО ВПО «Донецкий национальный медицинский университет им. М Горького 2)РОЦ «Республиканский онкологический центр» им. Профессора Г.В. Бондаря МЗ ДНР
  • М. Г. Мутык 2)РОЦ «Республиканский онкологический центр» им. Профессора Г.В. Бондаря
  • М. М. Клочков 1)ГОО ВПО «Донецкий национальный медицинский университет им. М Горького
  • Р. А. Аль-Баргути 1)ГОО ВПО «Донецкий национальный медицинский университет им. М Горького
  • А. С. Золотухин 1)ГОО ВПО «Донецкий национальный медицинский университет им. М Горького

Аннотация

Проведен обзор литературы существующих подходов к лечению рака прямой кишки у больных старческого возраста, выявлены недостатки выбора тактики оперативного лечения и предлагаемых консервативных пособий, результатом чего является преимущественно повсеместный отказ от радикальных первично-восстановительных и сфинктерсохраняющих вмешательств. Проанализированы шкалы и методы оценки риска осложнений при консервативном и хирургическом лечении гериатрических больных колоректальным раком.

Литература

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17. Sanoff H.K., Goldberg R.M. Colorectal cancer treatment in older patients. Gastrointest Cancer Res 2007;1(6): 248-53.

18.Brooks M.J., Sutton R., Sarin S. Compar-ison of Surgical Risk Score, POSSUM and p-POSSUM in higher-risk surgical pa-tients. Br J Surg 2005;92(10):1288–92. DOI: 10.1002/bjs.5058. PMID: 15981213.

19.Kenisand C., Wildiers H., Wedding U. et al. Practice guideline. Comprehensive Geriatric Assessment (CGA) in oncologi-cal patients. 2011.

20.Teeuwen P.H., Bremers A.J., Groene-woud J.M. et al. Predictive value of POSSUM and ACPGBI scoring in mortality and morbidity of colorectal resection: a case-control study. J Gastroin-test Surg 2011;15(2):294–303. DOI: 10.1007/s11605-010-1354-0.

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24. Larsen S. G., Wiig J. N., Tretli S. et al. Surgery and preoperative irradiation for locally advanced or reccurent rectal cancer in patients over 75 years of age // Colorectal Dis. 2006. Vol. 8, № 3.P. 177-185. https://doi.org/10.1111/j.1463-1318.2005.00877.x

25. Ramesh H.S., Pope D., Gennari R., Audisio R.A. Optimising surgical management of elderly cancer patients. World J SurgOncol 2005;3(1):17.https://doi.org/10.1186/1477-7819-3-17.

26. Sun W. Management and outcome of colorectal cancer in elderly patients. Clin Colorectal Cancer 2003;3(3):172-3.https://doi.org/10.1016/S1533-0028(11)70085-8.

27.Frenkel W.J., Jongerius E.J., Mandjes-van Uitert M.J. et al. Validation of the Charl-son Comorbidity Index in acutely hospital-ized elderly adults: a prospective cohort study. J Am Geriatr Soc 2014;62(2):342–6. DOI: 10.1111/jgs.12635.

28. Graça Pereira M., Figueiredo A.P.,Fin-cham F.D. Anxiety, depression, traumatic stress and quality of life in colorectal can-cer after different treatments: A study with Portuguese patients and their partners. Eur J Oncol Nurs 2011;16(3):227–32. DOI: 10.1016/j.ejon.2011.06.006.

29.Larrabee G.J., Crook T.M. 3rd. Estimated prevalence of age associated memory im-pairment derived from standardized tests of memory function. Int Psychogeriatr 1994;6(1):95–104. PMID: 8054499.

30.Potash M., Breibart W. Affective disorders in advanced cancer. Hematol OncolClinNorthAm2002;16(3):671–700. PMID: 12170575.

31.Tan K.Y., Kawamura Y.,Mizokami K. et al. Colorectal surgery in octogenarian patients– outcomes and predictors of morbidity. Int J Colorectal Dis 2009;24(2):185–9. DOI: 10.1007/s00384-008-0615-9.

32.Charlson M., Szatrowski T.P., Peterson J., Gold J. Validation of a combined comor-bidity index. J Clin Epidemiol 1994;47(11):1245–51.

33.Slim K., Panis Y., Alves A. et al. Predicting postoperative mortality in patients under-going colorectal surgery. World J Surg 2006;30(1):100–6. DOI: 10.1007/s00268-005-0081-2. PMID: 16369701.

34.Benson A.B. 3rd,Venook A.P.,Cederquist L. et al. Colon cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw2017;15(3):370–98. PMID: 28275037.

35.Burhenn P.S., McCarthy A.L., Begue A. Geriatric assessment in daily oncology practice for nurses and allied health care professionals: Opinion paper of the Nurs-ing and Allied Health Interest Group of the International Society of Geriatric Oncology (SIOG). J Geriatr Oncol 2016;7(5):315–24. DOI: 10.1016/j.jgo.2016.02.006.

36.Decoster L., Van Puyvelde K., Mohile S. et al. Screening tools for multidimensional health problems warranting a geriatric as-sessment in older cancer patients: an up-date on SIOG recommendations. Ann Oncol 2015;26(2):288–300. DOI: 10.1093/annonc/mdu210.

37.Sandstrom R., Drott C., Hyltander A. et al. The effect of postoperative intrave-nous feeding (TPN) on outcome following major surgery evaluated in a randomized study. Ann Surg 1993;217(2):185–95. PMID: 8439216.

38.Сorreia M.I., Caiaffa W.T., da Silva A.L., Waitzberg D.L. Risk factors for malnutri-tion in patients undergoing gastroentero-logical and hernia surgery: an analysis of 374 patients. Nutr Hosp 2001;16(2): 59–64. PMID: 11443835.

39. Bozzetti F.,Forbes A. The ESPEN clinical practice Guidelines on Parenteral Nutrition: present status and perspectives for future re-search. Clin Nutr 2009;28(4):359–64. DOI: 10.1016/j.clnu.2009.05.010.

40. Egenvall M., Schubert Samuelsson K., Klarin I. et al. Management of colorectal cancer in the elderly: a population –based study // Colorectal Dis. – 2014. – Vol. 16, No 6. – P. 433–441. https://doi.org/10.1111/codi.12575

41.NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Rectal Cancer. Version 2.2017. NCCN Evidence Blokcs. 2017.

42.Kaiser M.J., Bauer J.M., Ramsch C. et al. Validation of the Mini Nutritional Assess-ment Short-Form (MNA-SF): A practical tool for identification of nutritional status. J Nutr Health Aging 2009;13(9):782–8. PMID: 19812868.

43.Lovenstone S., Gauthier S. Management of dementia. London: Martin Dunitz, 2001. P. 201.

44.Damhuis R.A., Meurs C.J., Meijer W.S. Postoperative mortality after cancer surgery in octogenarians and nonagenarians: results from a series of 5390 patients. // World J. SurgOncol. – 2005, No 3. – P. 71. https://doi.org/10.1016/S1359-6349(03)90249-7.

45.Nanayakkara C., Lekamwasam S. Validity of the 5-item Barthel Index in the assess-ment of physical dependence in the elder-ly. Asian J Gerontol Geriatr 2015;10(2):79–82.

46.Carmack C.L., Basen-Engquist K., Yuan Y. et al. Feasibility of an expressive-disclo-sure group intervention for post-treatment colorectal cancer patients: results of the Healthy Expressions study. Cancer 2011;117(21):4993–5002.DOI: 10.1002/cncr.26110.

47.Berardi D., Menchetti M., De Ronchi D. et al. Late-life depression in primary care: A nationwide Italian epidemiological sur-vey. J Am Geriatr Soc 2002;50(1):77–83. PMID: 12028250.

48.Zabora J., Brintzenhofeszoc K., Curbow B.et al. The prevalence of psychological dis-tress by cancer site. Psychooncology 2001;10(1):19–28. PMID: 11180574

49.Miranda D.O., Soares de Lima T.A., Aze-vedo L.R. et al. Proinflammatory cyto-kines correlate with depression and anxi-ety in colorectal cancer patients. Bio Med Res Int 2014;2014:739650. DOI: 10.1155/2014/739650.

50.Hurria A., Togawa K., Mohile S.G. Predict-ing chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011;29(25):3457–65. DOI: 10.1200/JCO.2011.34.7625.



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24. Larsen S. G., Wiig J. N., Tretli S. et al. Surgery and preoperative irradiation for locally advanced or reccurent rectal cancer in patients over 75 years of age // Colorectal Dis. 2006. Vol. 8, № 3.P. 177-185. https://doi.org/10.1111/j.1463-1318.2005.00877.x
25. Ramesh H.S., Pope D., Gennari R., Audisio R.A. Optimising surgical management of elderly cancer patients. World J SurgOncol 2005;3(1):17. https://doi.org/10.1186/1477-7819-3-17.
26. Sun W. Management and outcome of colorectal cancer in elderly patients. Clin Colorectal Cancer 2003;3(3):172-3.https://doi.org/10.1016/S1533-0028(11)70085-8.
27.Frenkel W.J., Jongerius E.J., Mandjes-van Uitert M.J. et al. Validation of the Charl-son Comorbidity Index in acutely hospital-ized elderly adults: a prospective cohort study. J Am Geriatr Soc 2014;62(2):342–6. DOI: 10.1111/jgs.12635.
28. Graça Pereira M., Figueiredo A.P.,Fin-cham F.D. Anxiety, depression, traumatic stress and quality of life in colorectal can-cer after different treatments: A study with Portuguese patients and their partners. Eur J Oncol Nurs 2011;16(3):227–32. DOI: 10.1016/j.ejon.2011.06.006.
29.Larrabee G.J., Crook T.M. 3rd. Estimated prevalence of age associated memory im-pairment derived from standardized tests of memory function. Int Psychogeriatr 1994;6(1):95–104. PMID: 8054499.
30.Potash M., Breibart W. Affective disorders in advanced cancer. Hematol OncolClinNorthAm2002;16(3):671–700. PMID: 12170575.
31.Tan K.Y., Kawamura Y.,Mizokami K. et al. Colorectal surgery in octogenarian patients– outcomes and predictors of morbidity. Int J Colorectal Dis 2009;24(2):185–9. DOI: 10.1007/s00384-008-0615-9.
32.Charlson M., Szatrowski T.P., Peterson J., Gold J. Validation of a combined comor-bidity index. J Clin Epidemiol 1994;47(11):1245–51.
33.Slim K., Panis Y., Alves A. et al. Predicting postoperative mortality in patients under-going colorectal surgery. World J Surg 2006;30(1):100–6. DOI: 10.1007/s00268-005-0081-2. PMID: 16369701.
34.Benson A.B. 3rd,Venook A.P.,Cederquist L. et al. Colon cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw2017;15(3):370–98. PMID: 28275037.
35.Burhenn P.S., McCarthy A.L., Begue A. Geriatric assessment in daily oncology practice for nurses and allied health care professionals: Opinion paper of the Nurs-ing and Allied Health Interest Group of the International Society of Geriatric Oncology (SIOG). J Geriatr Oncol 2016;7(5):315–24. DOI: 10.1016/j.jgo.2016.02.006.
36.Decoster L., Van Puyvelde K., Mohile S. et al. Screening tools for multidimensional health problems warranting a geriatric as-sessment in older cancer patients: an up-date on SIOG recommendations. Ann Oncol 2015;26(2):288–300. DOI: 10.1093/annonc/mdu210.
37.Sandstrom R., Drott C., Hyltander A. et al. The effect of postoperative intrave-nous feeding (TPN) on outcome following major surgery evaluated in a randomized study. Ann Surg 1993;217(2):185–95. PMID: 8439216.
38.Сorreia M.I., Caiaffa W.T., da Silva A.L., Waitzberg D.L. Risk factors for malnutri-tion in patients undergoing gastroentero-logical and hernia surgery: an analysis of 374 patients. Nutr Hosp 2001;16(2): 59–64. PMID: 11443835.
39. Bozzetti F.,Forbes A. The ESPEN clinical practice Guidelines on Parenteral Nutrition: present status and perspectives for future re-search. Clin Nutr 2009;28(4):359–64. DOI: 10.1016/j.clnu.2009.05.010.
40. Egenvall M., Schubert Samuelsson K., Klarin I. et al. Management of colorectal cancer in the elderly: a population –based study // Colorectal Dis. – 2014. – Vol. 16, No 6. – P. 433–441. https://doi.org/10.1111/codi.12575
41.NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Rectal Cancer. Version 2.2017. NCCN Evidence Blokcs. 2017.
42.Kaiser M.J., Bauer J.M., Ramsch C. et al. Validation of the Mini Nutritional Assess-ment Short-Form (MNA-SF): A practical tool for identification of nutritional status. J Nutr Health Aging 2009;13(9):782–8. PMID: 19812868.
43.Lovenstone S., Gauthier S. Management of dementia. London: Martin Dunitz, 2001. P. 201.
44.Damhuis R.A., Meurs C.J., Meijer W.S. Postoperative mortality after cancer surgery in octogenarians and nonagenarians: results from a series of 5390 patients. // World J. SurgOncol. – 2005, No 3. – P. 71. https://doi.org/10.1016/S1359-6349(03)90249-7.
45.Nanayakkara C., Lekamwasam S. Validity of the 5-item Barthel Index in the assess-ment of physical dependence in the elder-ly. Asian J Gerontol Geriatr 2015;10(2):79–82.
46.Carmack C.L., Basen-Engquist K., Yuan Y. et al. Feasibility of an expressive-disclo-sure group intervention for post-treatment colorectal cancer patients: results of the Healthy Expressions study. Cancer 2011;117(21):4993–5002.DOI: 10.1002/cncr.26110.
47.Berardi D., Menchetti M., De Ronchi D. et al. Late-life depression in primary care: A nationwide Italian epidemiological sur-vey. J Am Geriatr Soc 2002;50(1):77–83. PMID: 12028250.
48.Zabora J., Brintzenhofeszoc K., Curbow B.et al. The prevalence of psychological dis-tress by cancer site. Psychooncology 2001;10(1):19–28. PMID: 11180574
49.Miranda D.O., Soares de Lima T.A., Aze-vedo L.R. et al. Proinflammatory cyto-kines correlate with depression and anxi-ety in colorectal cancer patients. Bio Med Res Int 2014;2014:739650. DOI: 10.1155/2014/739650.
50.Hurria A., Togawa K., Mohile S.G. Predict-ing chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011;29(25):3457–65. DOI: 10.1200/JCO.2011.34.7625.
Опубликована
2020-11-30
Как цитировать
ЗОЛОТУХИН, С. Э. et al. Проблемы лечения рака прямой кишки у больных старческого возраста. Новообразование, [S.l.], v. 12, n. 4, p. 126-132, ноя. 2020. ISSN 2521-117X. Доступно на: <http://donetsk-onco.com/neoplasm/index.php/Neoplasm/article/view/340>. Дата доступа: 18 янв. 2021 doi: https://doi.org/10.26435/neoplasm.v12i4.340.
Раздел
Обзоры литературы

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