Значение эластографии в реальном времени в диагностике рака простаты
Аннотация
Цель: оценить клиническую значимость трансректальной эластографии в реальном времени (TРЭ) в диагностике рака предстательной железы (PПЖ).
Методы: в исследование были включены 195 пациентов с повышенным уровнем ПСА. Анализ кривой ошибок (ROC) проводился для оценки диагностической эффективности TРЭ.
Результаты: баллы TРЭ у пациентов с PПЖ и доброкачественным состоянием составляли 3,20 ± 1,11 (диапазон: 1–5) и 2,24 ± 1,01 (диапазон: 1–4), соответственно (P <0,001). Наилучшее пороговое значение показателя TРЭ составило 3, а чувствительность, специфичность, точность в диагностике РПЖ составили 68,6% (35/51), 69,4% (100/144) и 69,2% (135/195), соответственно. Точность TРЭ при объеме ПЖ ≤30 мл была значительно выше, чем в группе объема ≥50 мл и в группе 30–50 мл (76,9% против 65,0% и 76,9% против 71,4%, в обеих группах P <0,001). Точность оценки TРЭ была выше для пациентов с ПСА в диапазоне 4–10 нг/мл, чем для пациентов с ПСА > 10 нг/мл (85,3% против 66,7%, P = 0,002).
Вывод: полуколичественная оценка жесткости предстательной железы может служить полезным методом скрининга для пациентов с подозрением PПЖ, особенно для тех, у которых повышенный уровень ПСА не сопровождается клиническими проявлениями.
Литература
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15. Ophir J, Cespedes I, Ponnekanti H, Yazdi Y and Li X. Elastography: a quantitative method for imaging the elasticity of biological tissues. Ul-trason Imaging 1991; 13: 111-134.
16. Kamoi K, Okihara K, Ochiai A, Ukimura O, Mizutani Y, Kawauchi A and Miki T. The utility of transrectal real-time elastography in the diag-nosis of prostate cancer. Ultrasound Med Biol. 2008; 34: 1025-1032.
17. Ferrari FS, Scorzelli A, Megliola A, Drudi FM, Trovarelli S and Ponchietti R. Real-time elas-tography in the diagnosis of prostate tumor. J Ultrasound 2009; 12: 22-31.
Wei Jin, Xiang Fei, Xia Wang, Yan Song, Fangjie Chen. Mediators Inflamm. 2020; 2020: 8730608. Published online 2020 May 4. doi: 10.1155/2020/8730608
2. Extended follow-up for prostate cancer incidence and mortality in the PLCO randomized cancer screening trial. Pinsky PF, Miller E.A, Prorok P, Grubb R, Crawford ED, Andriole G. BJU Int. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: BJU Int. 2019 May; 123(5): 854–860. Published online 2018 Nov 2. doi: 10.1111/bju.14580
3. Impact of PSA threshold and screening interval in prostate cancer screening outcomes – Comparing the Swedish and Finnish ERSPC centres. Lasse Saarimäki, Jonas Hugosson, Teuvo L Tammela, Sigrid Carlsson, Kirsi Talala, Anssi Auvinen. Eur Urol Focus. Author manuscript; available in PMC 2020 Mar 1. Published in final edited form as: Eur Urol Focus. 2019 Mar; 5(2): 186–191. Published online 2017 Aug 10. doi: 10.1016/j.euf.2017.07.007
4. Early Diagnosis of Prostate Cancer from the Perspective of Chinese Physicians
Wei Yu, Liqun Zhou. J Cancer. 2020; 11(11): 3264–3273. Published online 2020 Mar 5. doi: 10.7150/jca.36697
5. Can epigenetic and inflammatory biomarkers identify clinically aggressive prostate cancer?
Pedro Bargão Santos, Hitendra Patel, Rui Henrique, Ana Félix. World J Clin Oncol. 2020 Feb 24; 11(2): 43–52. Published online 2020 Feb 24. doi: 10.5306/wjco.v11.i2.43
6. Is dynamic contrast enhancement still necessary in multiparametric magnetic resonance for diagnosis of prostate cancer: a systematic review and meta-analysis. Zhen Liang, Rui Hu, Yongjiao Yang, Neng An, Xiaoxin Duo, Zheng Liu, Shangheng Shi, Xiaoqiang Liu. Transl Androl Urol. 2020 Apr; 9(2): 553–573. doi: 10.21037/tau.2020.02.03
7. Stiffness of prostate gland measured by transrectal real-time shear wave elastography for detection of prostate cancer: a feasibility study. Yonghao Ji, Litao Ruan, Wei Ren, Guoliang Dun, Jianxue Liu, Yaoren Zhang, Qinyun Wan. Br J Radiol. 2019 May; 92(1097): 20180970. Published online 2019 Mar 21. doi: 10.1259/bjr.20180970
8. Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules. Shufang Pei, Bin Zhang, Shuzhen Cong, Juanjuan Liu, Suqing Wu, Yuhao Dong, Lu Zhang, Shuixing Zhang. Int J Endocrinol. 2020; 2020: 1749351. Published online 2020 Apr 14. doi: 10.1155/2020/1749351
9. Impact of a novel ultrasound microvascular imaging and elastography on prostate cancer classification. Ting-Ting Shen, Jun-Li Xue
Transl Androl Urol. 2019 Dec; 8(6): 696–702. doi: 10.21037/tau.2019.11.15
10. Loeb S, Carter HB, Berndt SI, Ricker W and Schaeffer EM. Complications after prostate bi-opsy: data from SEER-Medicare. J Urol 2011; 186: 1830-1834.
11. Aigner F, Pallwein L, Junker D, Schafer G, Mi-kuz G, Pedross F, Mitterberger MJ, Jaschke W, Halpern EJ and Frauscher F. Value of real-time elastography targeted biopsy for prostate can-cer detection in men with prostate specific an-tigen 1.25 ng/ml or greater and 4.00 ng/ml or less. J Urol 2010; 184: 913-917
12. Cochlin DL, Ganatra RH and Griffiths DF. Elas-tography in the detection of prostatic cancer.
Clin Radiol 2002; 57: 1014-1020.
13. Nelson ED, Slotoroff CB, Gomella LG and Halp-ern EJ. Targeted biopsy of the prostate: the im-pact of color Doppler imaging and elastogra-phy on prostate cancer detection and Gleason score. Urology 2007; 70: 1136-1140.
14. Lane BR, Zippe CD, Abouassaly R, Schoenfield L, Magi-Galluzzi C and Jones JS. Saturation technique does not decrease cancer detection during followup after initial prostate biopsy. J Urol 2008; 179: 1746-1750; discussion 1750.
15. Ophir J, Cespedes I, Ponnekanti H, Yazdi Y and Li X. Elastography: a quantitative method for imaging the elasticity of biological tissues. Ul-trason Imaging 1991; 13: 111-134.
16. Kamoi K, Okihara K, Ochiai A, Ukimura O, Mizutani Y, Kawauchi A and Miki T. The utility of transrectal real-time elastography in the diag-nosis of prostate cancer. Ultrasound Med Biol. 2008; 34: 1025-1032.
17. Ferrari FS, Scorzelli A, Megliola A, Drudi FM, Trovarelli S and Ponchietti R. Real-time elas-tography in the diagnosis of prostate tumor. J Ultrasound 2009; 12: 22-31.
Опубликована
2021-04-06
Как цитировать
АЗАБ, Х. А.; РОДОВИЧ, В. В..
Значение эластографии в реальном времени в диагностике рака простаты.
Новообразование, [S.l.], v. 13, n. 1, p. 11-17, апр. 2021.
ISSN 2521-117X.
Доступно на: <http://donetsk-onco.com/neoplasm/index.php/Neoplasm/article/view/362>. Дата доступа: 19 апр. 2024
doi: https://doi.org/10.26435/neoplasm.v13i1.362.
Раздел
Оригинальные статьи
